ResMed AirSense 11 AutoSet CPAP Machine Review

Written by Tochukwu Ikpeze, MD Contributing Writer
Reviewed by Abhinav Singh, MD, MPH, FAASM Medical Reviewer
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The ResMed AirSense 11 AutoSet is a positive airway pressure (PAP) machine launched in 2021. It lets users choose between a continuous positive airway pressure (CPAP) mode, which delivers a fixed pressure level, and two automatic positive airway pressure (APAP) settings that use different algorithms to adjust air pressure levels based on the user’s breathing patterns.

In addition to various comfort settings and an integrated heated humidifier, the AirSense 11 AutoSet is compatible with ClimateLineAir 11 heated tubing and comes with access to ResMed’s myAir support program and app.

To help you decide whether the AirSense 11 AutoSet CPAP Machine is right for you, we’ll explain the machine’s features and what you should know before purchasing.

At a Glance

The ResMed AirSense 11 AutoSet is an advanced auto-adjusting CPAP machine that combines personalized pressure therapy with an integrated humidifier and user-friendly touchscreen.

Ideal For

  • People interested in automatic pressure adjustment, including first-time APAP users
  • Customers who appreciate advanced app integration and support
  • CPAP users who find their current machine uncomfortable to use

Who Should Keep Looking

  • People who want a simple machine with just a CPAP setting
  • CPAP users who don’t need a humidifier
  • Shoppers on a tight budget
  • Price

    $1,044

  • Dimensions

    3.72” x 10.71” x 5.45”

  • Noise Rating

    27 dBA

  • Weight

    2.3 lbs.

  • Warranty

    2 years

Use this SleepApnea.org link for the most current discount on the AirSense 11

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Our ResMed AirSense 11 AutoSet CPAP Machine Review

The ResMed AirSense 11 AutoSet has three PAP therapy modes. In addition to a fixed-pressure CPAP mode, the AutoSet and AutoSet for Her functions are APAP modes that automatically adjust the air pressure based on changes in breathing.

In addition to the automatic pressure adjustment, the AirSense 11 AutoSet has a number of settings to improve comfort. These include automatic ramp settings, air pressure reduction during exhalation, and a setting that provides gentler automatic pressure changes.

Like all CPAP and APAP machines, the AirSense 11 AutoSet can only be purchased with a prescription. Talk to your doctor if you think it may be a good fit for your needs.

What's Included

The AirSense 11 AutoSet features an integrated heated humidifier. The machine is compatible with the company’s ClimateLineAir 11 heated tubing, though it can also be used with standard tubing from ResMed or other brands. The temperature of both the humidifier and the heated tubing can be controlled by the user or set to automatically adjust to a comfortable temperature.

  • Standard and cleanable humidifier tanks
  • Filter
  • Tubing
  • Power supply with 65-watt AC adapter
  • Travel bag

Notable Features

The AirSense 11 AutoSet offers an array of comfort-focused features, as well as additional app integration to help improve the therapy experience.

  • Integrated heated humidifier and optional heated tubing: Many people find that dry, cool air can irritate their airway and lead to dry mouth or nasal congestion. The AirSense 11’s climate control features ensure that the pressurized air is comfortable to breathe and less likely to cause irritation.
  • Automatic ramp settings: Since falling asleep can be difficult for some people when a PAP machine is at full pressure, the AirSense 11 series offers settings that automatically ramp up to full pressure once the machine detects the user is asleep.
  • Reduced pressure during exhalation: Exhaling against pressurized air can feel uncomfortable and unnatural for many people, so ResMed has included an expiratory pressure relief (EPR) setting to reduce the air pressure during exhalation.
  • AutoSet Response comfort setting: This setting provides subtler transitions between automatic pressure changes, making the AirSense 11 AutoSet an attractive choice for first-time APAP users.
  • Wireless technology integration: ResMed’s myAir app provides users with support, troubleshooting, and access to therapy data. The machine can also receive wireless maintenance and updates.
  • Advanced event detection: The AirSense 11 AutoSet’s algorithm is able to detect breathing problems like central sleep apnea, Cheyne-Stokes respiration, and respiratory effort-related arousal.

Size and Cost

The AirSense 11 AutoSet is sleek and streamlined like many modern CPAP models. Measuring just over 10 inches across, with a depth of about 5.5 inches, it can easily fit on most night stands. Though it's larger than those marketed as travel CPAP machines, its 2.5-pound weight makes it relatively easy to travel with if needed.

Prices vary by retailer, but the cost of the AirSense 11 AutoSet is comparable to other machines with both APAP and CPAP capabilities.

  • Dimensions: 3.72” x 10.71” x 5.45”
  • Weight: 2.3 lbs.
  • Price: $1,044

Customer Reviews

Customer reviews for the ResMed AirSense 11 AutoSet have been very positive, with many experienced CPAP users reporting that they found the AirSense 11 AutoSet more intuitive to use than their previous model. ResMed’s myAir app also earned praise thanks to its clear data visualization and ease of use. 

Although customers have reported that the humidifier tank for the AirSense 11 is easier to clean than that of the AirSense 10, some have found it difficult to know for certain whether the tank was reinserted correctly.

Trial, Warranty, and Shipping Policies

AvailabilityThe ResMed AirSense 11 AutoSet is available through both brick-and-mortar and online CPAP retailers. A prescription is required to purchase the machine.
ShippingResMed doesn't sell its CPAP machines directly to consumers, so shipping times and fees will vary depending on the retailer you choose. Depending on your location, many online retailers offer free shipping for CPAP machine purchases.
Sleep TrialResMed doesn't offer a sleep trial for the AirSense 11 AutoSet. It's worth checking the return policies of the retailer you choose before making your purchase.
WarrantyThe AirSense 11 AutoSet has a two-year warranty covering manufacturing defects for both the machine and its humidifier. The cleanable water tank has a separate one-year warranty, while the tubing and standard water tank have 90-day warranties.

Other ResMed PAP Machines

  • ResMed AirSense 10 AutoSet: The ResMed AirSense 10 AutoSet is a premium auto-adjusting CPAP machine that pairs intelligent pressure adjustments with a built-in humidifier and heated tubing to optimize comfort and maintain consistent therapy throughout the night.
  • ResMed AirCurve 10 VAuto: ResMed's AirCurve 10 is a BiPAP machine that delivers bilevel therapy with separate pressures for inhaling and exhaling, offering enhanced comfort and support for users who need higher pressure or more advanced breathing assistance.
  • ResMed AirCurve 11 VAuto: The ResMed AirCurve 11 VAuto is an advanced bilevel device that automatically adjusts pressure levels and includes integrated humidification, providing personalized therapy and improved comfort for more complex sleep apnea needs.
  • ResMed AirMini: The ResMed AirMini is a compact, travel-friendly CPAP machine that delivers effective therapy in a lightweight design, making it easy to maintain treatment while on the go without sacrificing performance.

Frequently Asked Questions


The AirSense 11 AutoSet has a relatively intuitive touchscreen that most people should find easy to use, though people with motor control concerns may prefer a model that uses a dial. Data and settings are easily accessible through different touchscreen categories, while colorful icons show current settings and any warnings.

The AirSense 11 AutoSet is compatible with most ResMed masks. The company provides a list on its website of the machine’s compatibility with specific models. It may also be compatible with CPAP masks from other brands, but check with your doctor to ensure the mask is suitable for your needs.

It's also compatible with most standard tubing, but people who prefer heated tubing must use the ResMed ClimateLineAir 11 hose. The humidification system requires that you use ResMed’s standard or cleanable water tanks specific to this model.

CPAP air pressure is measured in centimeters of water pressure (cm H2O). The AirSense 11 AutoSet has a pressure range of 4 to 20 cm H2O, which is standard for most CPAP and APAP machines.

The AirSense 11 AutoSet has a sound level of around 27 decibels. This is slightly below average, as a typical CPAP sound level is about 30 decibels.

The AirSense 11 AutoSet features both manual and automatic climate control settings. The humidity level can be adjusted to settings ranging from 1 to 8 or turned off altogether. For AirSense 11 users who prefer the ClimateLineAir 11 heated tubing, the hose temperature can be set anywhere from 60 to 86 degrees Fahrenheit.

ResMed suggests that AirSense 11 AutoSet owners clean the hosing on a weekly basis and the humidifier tank daily. Other accessories, such as masks and headgear, should also be washed daily to maximize safety and effectiveness. CPAP accessories should be washed with warm water and mild soap. The company recommends replacing the air filter every six months at minimum.

While the AirSense 11 AutoSet is larger and heavier than travel CPAP machines, it's still small and lightweight enough for easy packing. The machine is also cleared by the Federal Aviation Administration for in-flight use, though it must be set to airplane mode and shouldn't be used with the humidifier in case of turbulence.

Still have questions?

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Written by

Tochukwu Ikpeze, MD, Contributing Writer

Tochukwu grew up in New York and has a passion for creative and scientific writing. Tochukwu holds an undergraduate degree in Biology and Psychology, a Master’s degree in Biomedical Science, and a Medical Degree as well. In his free time, Tochukwu enjoys reading, learning, exploring various topics pertaining to the human condition and conveying that information to the public through writing.

Reviewed by

Abhinav Singh, MD, MPH, FAASM, Medical Reviewer

Dr. Abhinav Singh is a board-certified sleep medicine physician and internist specializing in the diagnosis and treatment of sleep disorders, including obstructive sleep apnea, insomnia, narcolepsy, and excessive daytime sleepiness. He serves as the Medical Director of the Indiana Sleep Center, an American Academy of Sleep Medicine-accredited facility, where he helps patients improve their sleep and overall health through evidence-based care and patient education.