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3B Luna G3 BPAP 25A Machine Review

Written by Amber Garnett Staff Writer
Reviewed by Dr. Alberto Ramos Medical Reviewer
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Look & Feel

The Luna G3 BPAP 25A has a sleek and compact design with user-friendly front-facing navigation, a modern finish, and an integrated humidifier. The device comes with heated tubing for added comfort.

Ideal For

  • People looking for a machine with a built-in humidifier
  • Those who want to share therapy compliance data wirelessly
  • Sleepers who prefer a quiet machine

Who Should Keep Looking

  • Shoppers seeking a low-cost BiPAP machine without advanced features
  • Travelers looking to use their machine in-flight
  • People who want a machine that increases air output to compensate for leaks
  • Price

    $1,880

  • Dimensions

    10.4″ x 5.7″ x 4.5″

  • Noise Rating

    26 dBA

  • Weight

    3.75 lbs.

The Luna G3 BPAP 25A by React Health (formerly 3B Medical) is a compact bilevel positive airway pressure device — also known as a BiPAP or BPAP machine — that’s designed to treat sleep apnea.

Unlike a continuous positive airway pressure (CPAP) machine, which produces one fixed level of pressurized air, this Luna BiPAP machine delivers different air pressure levels for inhalation and exhalation.

We’ll examine this machine’s features and performance so you and your doctor can make an informed decision about whether it meets your needs.

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Other Models in the Luna Series

There are several other Luna models in React Health’s line of positive airway pressure (PAP) machines, including the Luna II Auto CPAP and the Luna G3 BPAP 30VT. Each device has unique features targeting specific therapy needs. 

  • Luna II Auto CPAP: This device in the Luna series is an automatic positive airway pressure (APAP) machine, meaning it automatically adjusts air pressure within a prescribed range based on the user’s breathing patterns. The design includes a top-mounted navigation system, heated humidification, and a ramp mode that gradually increases the air pressure when the machine is turned on. 
  • Luna G3 APAP: The Luna G3 APAP is an upgraded version of the Luna II. Front-facing navigation allows for easy adjustments, and it comes with heated tubing designed to prevent excess condensation from forming in the hose or your mask. 
  • Luna G3 BPAP 30VT: This top-of-the-line BiPAP machine has front-facing navigation and features several advanced algorithms, including a mode that helps you breathe if the machine detects that the user has stopped breathing for a set period of time.

What You Need to Know About the Luna G3 BPAP 25A Machine

As a BiPAP machine, the Luna G3 BPAP 25A delivers higher pressure when you breathe in and lower pressure when you breathe out. The two pressure levels are programmed based on a doctor’s prescription following a titration study.

The lower expiratory pressure feels more comfortable for some people, which is why BiPAP therapy is sometimes prescribed for those who have difficulty tolerating fixed-pressure CPAP therapy.

This Luna BiPAP machine has front-facing navigation, a built-in humidifier, and audible leak detection alerts. It also provides a breakdown of usage time, mask seal quality, and respiratory events, and this data can be transmitted over cellular networks or saved onto an SD card to share with your physician. You can set automatic reminders to change out your mask, tubing, and air filter. 

What Comes With It

The Luna G3 BPAP 25A includes an integrated humidifier that adds moisture to the air produced by the machine and heated tubing designed to prevent condensation. It also comes with a power cord, a reusable filter, an SD memory card to store data, and a carrying bag to keep the components organized.

Other accessories, like a nasal or full-face mask, must be purchased separately.

Features You Might Like

The Luna G3 BPAP 25A has a variety of special features. The integrated humidifier and ability to preheat the water lets users keep the air at a comfortable temperature and may help prevent nose and mouth dryness. Additionally, the heated tubing is designed to prevent condensation from traveling to the user’s mask.

The sleek design includes a front-facing navigation system with a clock. A knob with a button in its center is used to toggle through the device’s various functions.

This machine has a ramp feature, which means it can gradually increase the pressure level to ease into therapy when powering on the device. It also provides a usage score and summary so you can track and save important sleep data, including usage time, mask seal quality, and respiratory events. The cellular mode enables you to send sleep data to your health care provider through React Health’s iCodeConnect platform. 

Size and Cost of This Machine

The streamlined design of the Luna G3 BPAP 25A is optimized to fit easily on your bedside table, making it a great option for those with limited space. Additionally, the integrated humidifier reduces the size of this BiPAP machine, making it more compact and convenient for users. 

Weighing 3.75 pounds, this device is easy to carry and portable enough to fit into a backpack or suitcase. However, it is heavier than travel-specific PAP devices and is not designed for use on airplanes. 

BiPAP machines generally cost more than CPAP devices. While the Luna G3 BPAP 25A is more expensive than the typical CPAP machine, it’s on the lower end of the average price range for BiPAP models.

How This Luna BiPAP Machine Performs


The Luna G3 BPAP 25A includes a variety of features that contribute to the machine’s overall performance and user experience.

The machine’s user-friendly interface and digital screen make it easy to program and operate. Programmable resupply reminders provide added convenience.

The pressure range of the Luna G3 BPAP 25A is 4 to 25 centimeters of water pressure (cm H2O). This falls within the typical range for BiPAP devices, though some models go up to 30 cm H2O.

This Luna BiPAP machine emits a sound level around 26 decibels, which is quieter than a whisper and makes it an excellent option for noise-sensitive sleepers.

The Luna G3 BPAP 25A allows you to adjust the tubing temperature. There are five temperature options and an auto mode. The device also offers five humidity levels and includes the option of preheating the humidifier water.

Regular cleaning of your PAP machine is important to prevent illness. For this machine, you can find detailed cleaning instructions in the user manual. Make sure to unplug the device before disassembling components for cleaning. Use mild soap and warm water to clean the device’s washable components and let them thoroughly air dry before reusing them. The user manual contains replacement schedules for the device’s various components and accessories.

The Luna G3 BPAP 25A is compact and includes a carrying case for easy transport. Weighing 3.75 pounds, the machine is heavier than a typical travel PAP machine and does not come with a battery option. It is not approved for use during flights by the Federal Aviation Administration.

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What Do Customers Have to Say About the Luna G3 BPAP 25A Machine?

The Luna G3 BPAP 25A has received positive reviews from people who have found it to be reliable and user-friendly. Many appreciate the machine’s customizable temperature and humidity settings. 

A common issue mentioned by reviewers is the water chamber being small and difficult to clean. Overall, this Luna BiPAP machine is praised for its quiet operation, compact design, and the inclusion of a carrying case. 

Trial, Warranty, and Shipping Policies

AvailabilityLike all PAP machines, you need a prescription from your health care provider to purchase the Luna G3 BPAP 25A. It’s sold by various online retailers, including Sleep Doctor, as well as brick-and-mortar medical supply stores.
ShippingSleep Doctor offers free shipping in the contiguous U.S. via first-class or priority mail. Shipping fees apply to purchases in Alaska, Hawaii, and U.S. territories. Basic assembly is required, with detailed instructions included in the user manual.
ReturnsSleep Doctor accepts returns for unopened and unused products within 60 days of delivery. Customers are responsible for return shipping fees. Used PAP machines are ineligible for return.
WarrantyThe Luna G3 BPAP 25A comes with a two-year limited warranty for the main unit and a three-month limited warranty for accessories. Sleep Doctor does not offer a separate dealer warranty but will facilitate returns of defective machines to the manufacturer. Device owners are responsible for return shipping fees. The manufacturer will repair or replace any parts it deems defective and cover shipping charges to the dealer location.

Medical Disclaimer: This content is for informational purposes and does not constitute medical advice. Please consult a health care provider prior to starting a new treatment or making changes to your treatment plan.

Still have questions?

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Written by

Amber Garnett, Staff Writer

Amber is a freelance writer who resides in Seattle. Amber has worked as a clinical social worker in the medical field for over a decade. She loves long nature walks, traveling and reading poetry.

Reviewed by

Dr. Alberto Ramos, Medical Reviewer

Dr. Ramos is a Professor of Clinical Neurology and the Research Director of the sleep disorders program at the University of Miami, Miller School of Medicine. He mentors and trains physician scientists. As a McKnight Institute for Brain Research collaborator, he focuses on the intersection between sleep disorders, cerebrovascular disease, and neurocognitive aging in population-based studies. As an investigator, he has also been involved with the Northern Manhattan Study and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) since 2010.